Archives of Physical Medicine and Rehabilitation
Review article (meta-analysis)What Are the Important Factors in Health-Related Quality of Life for People With Aphasia? A Systematic Review
Section snippets
Methods
This review follows well-established methods for conducting and reporting systematic literature reviews.46, 47
Study Selection
Electronic database searches were conducted in September 2010 and resulted in a total of 2254 references. Nineteen references were received from requests for information from subject experts. Study flow in the review and reasons for exclusion are given in figure 1 (only 1 reason is given per excluded study, though in many cases studies could have been excluded for more than 1 reason). After deduplication, 1791 (79%) studies remained. The screening process resulted in the exclusion of 1746
Summary and Implications of Findings
Fourteen reports were found that reported factors associated with or predictive of HRQL in people with aphasia. Emotional distress/depression, extent of aphasic impairment and communication disability, presence of other medical problems, and activity level were the predictors of HRQL emerging from quantitative studies. Social factors also emerged as important. Themes drawn from qualitative studies—looking to the future/having a positive outlook, verbal communication, body functioning, and
Conclusions
Design and quality limitations of the included studies mean that the existing evidence is not strong enough to determine the main predictors of HRQL in people with aphasia poststroke. Factors that have consistently emerged as important are emotional distress/depression, extent of aphasic impairment and communication disability, and, to a lesser extent, presence of other medical problems, activity levels, and aspects of social network and support. There is a need for further research, first to
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