Clinical ResearchClinical Insights from Cardiac ImagingEffects of Aggressive Versus Conventional Lipid-Lowering Therapy by Simvastatin on Human Atherosclerotic Lesions: A Prospective, Randomized, Double-Blind Trial With High-Resolution Magnetic Resonance Imaging
Clinical Insights from Cardiac Imaging
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Abbreviations and Acronyms
CHD
coronary heart disease
HDL
high-density lipoprotein
IVUS
intravascular ultrasound
LA
lumen area
LDL-C
low-density lipoprotein cholesterol
MRI
magnetic resonance imaging
TC
total cholesterol
TE
echo time
TR
repetition time
TVA
total vessel area
VWA
vessel wall area
VWT
vessel wall thickness
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This study was supported by grants from the National Institutes of Health (HL54469, Drs. Fuster and Badimon); the National Heart, Lung, and Blood Institute (HL61801, Dr. Fuster); The Swiss National Research Foundation (Dr. Corti); The National Heart Foundation of Australia (Dr. Worthley); The French Federation of Cardiology (Dr. Helft); and Merck and Co, Inc. Merck and Co. was partially responsible for the funding of the project. Mount Sinai authors are fully responsible for data acquisition, evaluation, and writing the manuscript without any interference from the funding sources.
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Drs. Corti and Muntwyler are currently working in the Department of Cardiology, University Hospital Zurich, Switzerland.
Copyright © 2005 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.