Specific pre-existing conditions are linked to worse COVID-19 outcome.
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Whether Parkinson's disease (PD) poses an increased risk is unknown.
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117 PD patients with COVID-19 from in 21 centres in 4 country were analyzed.
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Mortality was 19.7%, with an effect of dementia, hypertension, and PD duration.
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The frailty caused by advanced PD increased the risk of mortality during COVID-19.
Abstract
Introduction
Specific pre-existing medical conditions (e.g. hypertension or obesity), advanced age and male sex appear linked to more severe manifestations of SARS Co-V2 infection, thus raising the question of whether Parkinson's disease (PD) poses an increased risk of morbidity and mortality in COVID-19 patients.
Methods
In order to describe the outcome of COVID-19 in multi-centre a cohort of PD patients and explore its potential predictors, we gathered the clinical information of 117 community-dwelling patients with COVID-19 followed in 21 tertiary centres in Italy, Iran, Spain, and the UK.
Results
Overall mortality was 19.7%, with a significant effect of co-occurrence of dementia, hypertension, and PD duration.
Conclusions
The frailty caused by advanced PD poses an increased risk of mortality during COVID-19.
