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Beyond recanalization — a call for action in acute stroke

Nature Reviews Neurology volume 16, pages 591–592 (2020)Cite this article

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Despite the strong treatment effects of mechanical thrombectomy in acute ischaemic stroke, penumbral tissue loss before recanalization and ischaemia–reperfusion injury after diminish functional outcomes and call for adjunct treatments. Classical neuroprotection strategies could consequently be revived, but novel treatment targets are also emerging through mechanistic research.

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Acknowledgements

Work cited in this comment was funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) Projektnummer 374031971 –TRR 240.

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Authors and Affiliations

  1. Department of Neurology, Würzburg University Hospital, Würzburg, Germany

    Guido Stoll

  2. Department of Neuroradiology, Würzburg University Hospital, Würzburg, Germany

    Mirko Pham

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  1. Guido Stoll
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  2. Mirko Pham
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Correspondence to Guido Stoll.

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Stoll, G., Pham, M. Beyond recanalization — a call for action in acute stroke. Nat Rev Neurol 16, 591–592 (2020). https://doi.org/10.1038/s41582-020-00417-0

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