Abstract
A Guillain-Barré syndrome patient showed giant negative T waves on electrocardiography at the height of the disease, with large left ventricular hypokinesis on echocardiography and extensive defects on 123I-meta-iodobenzylguanidine myocardial scintigraphy. Gamma-globulin improved the neurological symptoms, and the above abnormalities resolved. We speculate that cardiac sympathetic nerve endings were transiently damaged, with consequent myocardial injury, due to norepinephrine toxicity.
MeSH terms
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3-Iodobenzylguanidine / analogs & derivatives
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Aged
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Echocardiography / methods
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Female
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Guillain-Barre Syndrome / complications*
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Guillain-Barre Syndrome / physiopathology
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Heart / diagnostic imaging
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Humans
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Median Nerve / physiopathology
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Neural Conduction / physiology
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Peroneal Nerve / physiopathology
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Severity of Illness Index
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Sympatholytics
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Systole / physiology
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Tibial Nerve / physiopathology
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Tomography, Emission-Computed, Single-Photon
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Ventricular Dysfunction, Left / diagnosis*
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Ventricular Dysfunction, Left / etiology*
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Ventricular Dysfunction, Left / physiopathology
Substances
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Sympatholytics
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4-amino-3-iodobenzylguanidine
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3-Iodobenzylguanidine