Abstract
The authors investigated the effect of intermittent second-harmonic gray-scale (ISHGS) ultrasonography (US) with SH U 508A microbubbles on the conspicuity of focal liver lesions. Twenty-three patients were included in the study. Images were analyzed subjectively and quantitatively. Objective lesion conspicuity was increased. In 12 of the 15 patients with liver malignancy, gray-scale defects were seen in previously unsuspected areas. ISHGS US may improve the sensitivity of US for liver lesions.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Carcinoid Tumor / diagnostic imaging
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Carcinoma / diagnostic imaging
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Contrast Media* / administration & dosage
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Female
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Focal Nodular Hyperplasia / diagnostic imaging
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Humans
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Image Enhancement / methods*
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Image Processing, Computer-Assisted / methods
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Infusions, Intravenous
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Liver / diagnostic imaging
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Liver Neoplasms / diagnostic imaging*
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Liver Neoplasms / secondary
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Male
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Middle Aged
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Observer Variation
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Phantoms, Imaging
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Polysaccharides* / administration & dosage
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Sensitivity and Specificity
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Ultrasonics
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Ultrasonography
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Videotape Recording
Substances
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Contrast Media
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Polysaccharides
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SHU 508