Abstract
The genetics of Alzheimer's disease is one of the most complex topics to study from an epidemiological point of view, particularly in population-based studies on polymorphisms of genes. The present review focuses primarily on some conflicting results on genetic epidemiology of Alzheimer's disease, and the major difficulties met in such studies.
MeSH terms
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Alleles
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Alzheimer Disease / epidemiology
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Alzheimer Disease / genetics*
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Alzheimer Disease / pathology
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Alzheimer Disease / physiopathology
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Apolipoprotein E4
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Apolipoproteins E / genetics
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Brain / pathology
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Gene Frequency
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Genes, Dominant
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Genetic Predisposition to Disease
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Humans
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Prevalence
Substances
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Apolipoprotein E4
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Apolipoproteins E