Evidence for the validity and reliability of the ALS assessment questionnaire: the ALSAQ-40

C Jenkinson; R Fitzpatrick; C Brennan; M Swash

doi:10.1080/146608299300080022

Evidence for the validity and reliability of the ALS assessment questionnaire: the ALSAQ-40

Amyotroph Lateral Scler Other Motor Neuron Disord. 1999 Dec;1(1):33-40. doi: 10.1080/146608299300080022.

Authors

C Jenkinson¹, R Fitzpatrick, C Brennan, M Swash

Affiliation

¹ Health Services Research Unit, Division of Public Health & Primary Health Care, University of Oxford, Institute of Health Sciences, Headington, Oxford, OX3 7LF, UK.

PMID: 12365067
DOI: 10.1080/146608299300080022

Abstract

Objectives: The purpose of the study was to assess the validity and reliability of a new disease specific measure of health-related quality of life for ALS/MND: the 40-item ALS Assessment Questionnaire (ALSAQ-40).

Design: We carried out a longitudinal postal survey. The two administrations of the questionnaire were separated by 3 months.

Sample: Subjects were patients diagnosed with ALS/MND and registered with the UK MND Association.

Results: Dimensions of the ALSAQ-40 were shown to have high levels of internal reliability. The ALSAQ-40 was found to be sensitive to changes in self reported overall health state.

Conclusion: We concluded that the ALSAQ-40 has high levels of reliability and validity and can be used as an outcome measure in studies evaluating new treatment regimes and therapies.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amyotrophic Lateral Sclerosis* / physiopathology
Amyotrophic Lateral Sclerosis* / therapy
Humans
Longitudinal Studies
Quality of Life*
Reproducibility of Results
Surveys and Questionnaires*
Treatment Outcome