Transient mania with hypersexuality after surgery for high frequency stimulation of the subthalamic nucleus in Parkinson's disease

Mov Disord. 2002 Nov;17(6):1371-4. doi: 10.1002/mds.10265.

Abstract

Among 30 Parkinson's disease patients who received high frequency stimulation of the subthalamic nucleus, 5 developed remarkable disorders of mood or sexual behavior after the implant. We describe 2 men who developed mania and hypersexuality a few days after the implant that lasted for some months and then gradually disappeared spontaneously.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Arousal / physiology
  • Bipolar Disorder / diagnosis*
  • Bipolar Disorder / physiopathology
  • Dominance, Cerebral / physiology
  • Electric Stimulation Therapy*
  • Electrodes, Implanted
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Motivation
  • Neurologic Examination
  • Parkinson Disease / physiopathology
  • Parkinson Disease / therapy*
  • Postoperative Complications / diagnosis*
  • Postoperative Complications / physiopathology
  • Sexual Behavior / physiology*
  • Subthalamic Nucleus / physiopathology*