Spinal fusion in patients with Duchenne's muscular dystrophy and a low forced vital capacity

Eur Spine J. 2003 Oct;12(5):507-12. doi: 10.1007/s00586-003-0545-8. Epub 2003 May 14.

Abstract

Traditionally, spinal fusion has been denied to patients with scoliosis secondary to Duchenne's muscular dystrophy (DMD) when their forced vital capacity (FVC) is less than 30-40% of predicted values (PFVC). The reasons for this decision are a theoretically increased risk of adverse events from a prolonged anaesthetic and extensive surgery. This paper presents a retrospective analysis of 30 patients with DMD scoliosis who underwent posterior spinal fusion at the Royal National Orthopaedic Hospital. Two subgroups of patients were compared: those with more than 30% PFVC (17 patients) and those with less than 30% PVFC (13 patients). One patient in each group required a temporary tracheotomy and there were nine complications in total. The post-operative stay for patients in each group was similar (24 days in the >30% group, 20 days in the <30% group) and the complication rate was comparable with other published series. We conclude that spinal fusion can be offered to patients with DMD even in the presence of a low FVC.

MeSH terms

  • Adolescent
  • Adult
  • Anesthetics, General / adverse effects
  • Child
  • Humans
  • Length of Stay / statistics & numerical data
  • Male
  • Muscular Dystrophy, Duchenne / complications*
  • Patient Selection
  • Postoperative Complications / etiology
  • Postoperative Complications / physiopathology
  • Postoperative Complications / prevention & control
  • Respiratory Insufficiency / etiology*
  • Respiratory Insufficiency / physiopathology
  • Respiratory Insufficiency / surgery*
  • Retrospective Studies
  • Risk Factors
  • Scoliosis / complications*
  • Scoliosis / physiopathology
  • Scoliosis / surgery*
  • Spinal Fusion / adverse effects
  • Spinal Fusion / standards*
  • Treatment Outcome
  • Vital Capacity / physiology

Substances

  • Anesthetics, General