Botulinum toxin in a case of hemimasticatory spasm with severe worsening during pregnancy

Clin Neuropharmacol. 2004 Jan-Feb;27(1):6-8. doi: 10.1097/00002826-200401000-00004.

Abstract

Hemimasticatory spasm (HMS) is a rather uncommon movement disorder with a pathophysiology that is still unclear, although temporomasseter entrapment at the temporal fossa has been advanced. The authors present a case of HMS in a woman who experienced marked worsening in episode frequency and severity during pregnancy. Treatment with botulinum toxin led to marked improvement.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Adult
  • Anti-Dyskinesia Agents / therapeutic use*
  • Botulinum Toxins / therapeutic use*
  • Dose-Response Relationship, Drug
  • Electromyography / methods
  • Female
  • Hemifacial Spasm / drug therapy*
  • Humans
  • Masticatory Muscles / drug effects
  • Masticatory Muscles / physiopathology
  • Pregnancy
  • Pregnancy Complications / drug therapy*

Substances

  • Anti-Dyskinesia Agents
  • Botulinum Toxins