Neurotoxicity of cancer chemotherapy

Semin Neurol. 2004 Dec;24(4):419-26. doi: 10.1055/s-2004-861536.

Abstract

Neurological dysfunction is a common side effect of many chemotherapy drugs. For several agents neurotoxicity is common, severe, and can be dose-limiting. This is a review of the clinical features of chemotherapy-induced syndromes involving the central and peripheral nervous systems.

Publication types

  • Review

MeSH terms

  • Cerebrovascular Disorders / etiology
  • Dose-Response Relationship, Drug
  • Drug-Related Side Effects and Adverse Reactions*
  • Humans
  • Neoplasms / drug therapy
  • Nervous System Diseases / etiology
  • Neurotoxicity Syndromes / etiology*
  • Peripheral Nervous System Diseases / etiology