A systematic review of treatments for mild traumatic brain injury

Brain Inj. 2005 Oct;19(11):863-80. doi: 10.1080/02699050400025042.

Abstract

Objectives: To assess the effectiveness of interventions for mild traumatic brain injury (MTBI) in adults as found in the literature.

Research design: Systematic review of the literature.

Methods: Six electronic databases and 18 journals within the brain injury field were manually searched between the years 1980-2003. References from articles were scanned for further literature. Studies that met broad inclusion criteria were subjected to a formal test of relevance. Those found to be relevant were qualitatively tested for their methodological soundness.

Results: One thousand and fifty-five studies were initially identified and 163 were assessed using the relevance tool, yielding 20 studies for review. Four categories of interventions were identified: Pharmacotherapy, Cognitive Rehabilitation, Patient Education and Other. The majority of studies were weak, however there is evidence to support the effectiveness of patient education interventions.

Conclusions: There are few rigorous studies evaluating treatment of MTBI. Limitations of the current literature are presented.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Adult
  • Brain Injuries / etiology
  • Brain Injuries / psychology
  • Brain Injuries / therapy*
  • Cognition Disorders / etiology
  • Cognition Disorders / rehabilitation
  • Female
  • Humans
  • Male
  • Middle Aged
  • Patient Education as Topic / methods
  • Research Design
  • Trauma Severity Indices