Using the National Institutes of Health Stroke Scale (NIHSS) to predict the mortality and outcome of patients with intracerebral haemorrhage

Hong Kong Med J. 2008 Oct;14(5):367-70.

Abstract

Objectives: To investigate whether the National Institutes of Health Stroke Scale (NIHSS) can be used to predict mortality and functional outcome in patients presenting with intracerebral haemorrhage.

Design: Retrospective study of a prospectively collected cohort.

Setting: Regional hospital, Hong Kong.

Patients: A cohort of 359 patients presented to our hospital from 1996 to 2001 with their first-ever stroke and intracerebral haemorrhage.

Main outcome measures: The sensitivity and specificity of the NIHSS with a cut-off point of 20 in predicting mortality at 30 days and 5 years, and a favourable functional outcome at 5 years.

Results: A total of 359 patients were available for analysis and were divided into three subgroups according to the site and the size of the haematoma. The NIHSS can predict 30-day mortality with a sensitivity of 81% [corrected] and a specificity of 90% [corrected] The NIHSS can predict 5-year mortality with a sensitivity of 57% [corrected] and a specificity of 92% [corrected] In predicting favourable functional outcomes at 5 years, the NIHSS had a sensitivity of 98% [corrected] and a specificity of 16% [corrected]

Conclusions: The NIHSS performed on admission can be used to predict mortality at 30 days and 5 years as well as favourable functional outcome at 5 years, all with an acceptable sensitivity and specificity.

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Cerebral Hemorrhage / complications*
  • Female
  • Follow-Up Studies
  • Hong Kong / epidemiology
  • Humans
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care / methods*
  • Prospective Studies
  • Recurrence
  • Registries
  • Retrospective Studies
  • Sensitivity and Specificity
  • Severity of Illness Index*
  • Stroke / etiology
  • Stroke / mortality*