Neurologic manifestations of systemic lupus erythematosus in children and adults

Neurol Clin. 2010 Feb;28(1):61-73. doi: 10.1016/j.ncl.2009.09.004.

Abstract

Among the collagen vascular diseases neurologic manifestations have been most commonly recognized and well-studied in systemic lupus erythematosus (SLE, lupus). Neurologic manifestations are less prevalent in other systemic inflammatory and autoimmune disorders. This review focuses on the clinical presentation, pathophysiology, and treatment strategies of neuropsychiatric lupus (NPSLE) in children and adults.

Publication types

  • Review

MeSH terms

  • Adult
  • Animals
  • Brain / pathology
  • Child
  • Humans
  • Lupus Erythematosus, Systemic / diagnosis
  • Lupus Erythematosus, Systemic / epidemiology
  • Lupus Erythematosus, Systemic / pathology*
  • Lupus Erythematosus, Systemic / physiopathology*
  • Lupus Vasculitis, Central Nervous System / diagnosis
  • Lupus Vasculitis, Central Nervous System / epidemiology
  • Lupus Vasculitis, Central Nervous System / pathology
  • Lupus Vasculitis, Central Nervous System / physiopathology
  • Nervous System Diseases / diagnosis
  • Nervous System Diseases / epidemiology
  • Nervous System Diseases / pathology*
  • Nervous System Diseases / physiopathology*
  • Peripheral Nervous System Diseases / diagnosis
  • Peripheral Nervous System Diseases / epidemiology
  • Peripheral Nervous System Diseases / pathology
  • Peripheral Nervous System Diseases / physiopathology
  • Prevalence