Trigeminal nerve stimulation: seminal animal and human studies for epilepsy and depression

Christopher M DeGiorgio; Erika E Fanselow; Lara M Schrader; Ian A Cook

doi:10.1016/j.nec.2011.07.001

Trigeminal nerve stimulation: seminal animal and human studies for epilepsy and depression

Neurosurg Clin N Am. 2011 Oct;22(4):449-56, v. doi: 10.1016/j.nec.2011.07.001.

Authors

Christopher M DeGiorgio¹, Erika E Fanselow, Lara M Schrader, Ian A Cook

Affiliation

¹ Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. cmd@mednet.ucla.edu

PMID: 21939843
DOI: 10.1016/j.nec.2011.07.001

Abstract

The unique ability to stimulate bilaterally, extracranially, and non-invasively may represent a significant advantage to invasive neuromodulation therapies. In humans thus far the technique has been applied noninvasively, and is termed external trigeminal nerve stimulation (eTNSTM).

Publication types

Comparative Study
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Depressive Disorder / physiopathology
Depressive Disorder / therapy*
Electric Stimulation Therapy / instrumentation*
Electric Stimulation Therapy / methods*
Epilepsy / physiopathology
Epilepsy / therapy*
Humans
Trigeminal Nerve / physiology*
Trigeminal Nerve / surgery*