Abstract
Myoclonus in association with dementia of later adult life has been considered almost pathognomonic of Creutzfeldt-Jakob disease. However, myoclonus may also be seen with Alzheimer disease, and when the myoclonus occurs as an early manifestation of Alzheimer disease, distinction from Creutzfeldt-Jakob disease may prove difficult.
Publication types
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Case Reports
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Aged
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Alzheimer Disease / complications*
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Alzheimer Disease / diagnosis
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Alzheimer Disease / pathology
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Creutzfeldt-Jakob Syndrome / diagnosis
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Dementia / complications*
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Diagnosis, Differential
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Hippocampus / pathology
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Humans
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Male
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Myoclonus / etiology*
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Neurofibrils / pathology