This study examined the inter-relationships between employment status, employment experiences, background, educational and epilepsy-related variables in a community sample of 1709 people with epilepsy in England and Wales. A postal questionnaire yielded information which included attitudes to careers advice, experiences with fellow employees and management when in work, experiences of being questioned about epilepsy, and the perceived effect of having epilepsy on employment prospects. In a principal components analysis, a factor of 'employability' was identified that had high loadings for educational qualifications, socioeconomic status and employment history. Good employability was found to be related to perceptions that epilepsy had little or no effect on job prospects, good experiences with work colleagues and management, low seizure severity and good seizure control. Further data analyses which focused on people's actual employment histories confirmed the importance of past experiences in employment, educational qualifications, seizure severity and seizure frequency for distinguishing between groups. The study findings are discussed and, taken together, they imply that quality of medical care, employability and good employment history are interconnected in important ways.