Alzheimer's disease compared with cerebrovascular dementia. Neuropsychological similarities and differences

Acta Neurol Scand. 1993 Apr;87(4):299-308. doi: 10.1111/j.1600-0404.1993.tb05512.x.

Abstract

Forty-eight patients with a clinical diagnosis of Alzheimer's disease, 30 patients with cerebrovascular dementia, and 48 normal controls were assessed with a battery of neuropsychological tests designed to measure the following cognitive processes: orientation to time and place, memory, visual-perceptual and constructional skills, language, conceptualization, attention, and executive functions (planning, self-regulation and fine motor coordination). The differences detected were in orientation to time and place, in immediate and delayed recall of a short story, and in naming in which the patients with Alzheimer's disease were significantly disadvantaged. Vice versa, in attention processes, self-regulation, planning, and fine motor coordination tasks the patients with cerebrovascular dementia were more severely impaired; these disturbances resemble some of those occurring in frontal lobe syndromes.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Aged
  • Alzheimer Disease / complications
  • Alzheimer Disease / diagnosis*
  • Alzheimer Disease / physiopathology
  • Brain / physiopathology
  • Brain Diseases / diagnosis
  • Brain Diseases / physiopathology
  • Cognition Disorders / complications
  • Cognition Disorders / diagnosis
  • Cognition Disorders / physiopathology
  • Dementia, Vascular / complications
  • Dementia, Vascular / diagnosis*
  • Dementia, Vascular / physiopathology
  • Diagnosis, Differential
  • Female
  • Frontal Lobe / physiopathology
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Neuropsychological Tests*
  • Severity of Illness Index