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Page 1
Exome sequencing of individuals with Huntington's disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset.
McAllister B, Donaldson J, Binda CS, Powell S, Chughtai U, Edwards G, Stone J, Lobanov S, Elliston L, Schuhmacher LN, Rees E, Menzies G, Ciosi M, Maxwell A, Chao MJ, Hong EP, Lucente D, Wheeler V, Lee JM, MacDonald ME, Long JD, Aylward EH, Landwehrmeyer GB, Rosser AE; REGISTRY Investigators of the European Huntington’s disease network; Paulsen JS; PREDICT-HD Investigators of the Huntington Study Group; Williams NM, Gusella JF, Monckton DG, Allen ND, Holmans P, Jones L, Massey TH. McAllister B, et al. Among authors: elliston l. Nat Neurosci. 2022 Apr;25(4):446-457. doi: 10.1038/s41593-022-01033-5. Epub 2022 Apr 4. Nat Neurosci. 2022. PMID: 35379994 Free PMC article.
Huntingtin Exists as Multiple Splice Forms in Human Brain.
Mort M, Carlisle FA, Waite AJ, Elliston L, Allen ND, Jones L, Hughes AC. Mort M, et al. Among authors: elliston l. J Huntingtons Dis. 2015;4(2):161-71. doi: 10.3233/JHD-150151. J Huntingtons Dis. 2015. PMID: 26397897
Molecular analysis of the genotype-phenotype relationship in factor X deficiency.
Millar DS, Elliston L, Deex P, Krawczak M, Wacey AI, Reynaud J, Nieuwenhuis HK, Bolton-Maggs P, Mannucci PM, Reverter JC, Cachia P, Pasi KJ, Layton DM, Cooper DN. Millar DS, et al. Among authors: elliston l. Hum Genet. 2000 Feb;106(2):249-57. doi: 10.1007/s004390051035. Hum Genet. 2000. PMID: 10746568
Regional and cellular gene expression changes in human Huntington's disease brain.
Hodges A, Strand AD, Aragaki AK, Kuhn A, Sengstag T, Hughes G, Elliston LA, Hartog C, Goldstein DR, Thu D, Hollingsworth ZR, Collin F, Synek B, Holmans PA, Young AB, Wexler NS, Delorenzi M, Kooperberg C, Augood SJ, Faull RL, Olson JM, Jones L, Luthi-Carter R. Hodges A, et al. Among authors: elliston la. Hum Mol Genet. 2006 Mar 15;15(6):965-77. doi: 10.1093/hmg/ddl013. Epub 2006 Feb 8. Hum Mol Genet. 2006. PMID: 16467349
MAP kinase phosphatase 1 (MKP-1/DUSP1) is neuroprotective in Huntington's disease via additive effects of JNK and p38 inhibition.
Taylor DM, Moser R, Régulier E, Breuillaud L, Dixon M, Beesen AA, Elliston L, Silva Santos Mde F, Kim J, Jones L, Goldstein DR, Ferrante RJ, Luthi-Carter R. Taylor DM, et al. Among authors: elliston l. J Neurosci. 2013 Feb 6;33(6):2313-25. doi: 10.1523/JNEUROSCI.4965-11.2013. J Neurosci. 2013. PMID: 23392662 Free PMC article.
Similar striatal gene expression profiles in the striatum of the YAC128 and HdhQ150 mouse models of Huntington's disease are not reflected in mutant Huntingtin inclusion prevalence.
Bayram-Weston Z, Stone TC, Giles P, Elliston L, Janghra N, Higgs GV, Holmans PA, Dunnett SB, Brooks SP, Jones L. Bayram-Weston Z, et al. Among authors: elliston l. BMC Genomics. 2015 Dec 21;16:1079. doi: 10.1186/s12864-015-2251-4. BMC Genomics. 2015. PMID: 26691352 Free PMC article.
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