Thrombolysis with alteplase administered within a narrow therapeutic window provides an
effective therapy for acute ischaemic stroke. However, mainly because of prehospital delay …

Initially, hydroxyethyl starch (HES) was only characterized by its in vitro molecular weight
(MW). This is not sufficient because HES is degraded in vivo. One relevant parameter that …

Acute stroke is one of the main causes of death and chronic disability. Thrombolysis with
recombinant tissue plasminogen activator within the first hours after onset of symptoms is an …

Summary Background Only 2–5% of patients who have a stroke receive thrombolytic
treatment, mainly because of delay in reaching the hospital. We aimed to assess the efficacy …

Background and Purpose—The purpose of this study was to demonstrate a new approach to
the use of a self-expanding stent in the treatment of acute ischemic stroke. Methods—Twenty …

Background and purpose The purpose of this study was to assess the initial post-market
experience of the device and how it is compared with the Penumbra Pivotal trial used to …

Background Early treatment with rt-PA is critical for favorable outcome of acute stroke.
However, only a very small proportion of stroke patients receive this treatment, as most …

Objectives: The purpose of this study is to demonstrate the technical success of carotid
artery stenting in acute extracranial internal carotid artery (ICA) occlusion as well as the …

The plasma clearance of hydroxyethyl starch (HES) depends on the initial molecular weight
and the degree of substitution. So far, little attention has been paid to the clinical relevance …

Background: Recently, a strategy for treating stroke directly at the emergency site was
developed. It was based on the use of an ambulance equipped with a scanner, a point-of …