User profiles for "author:Alan King Lun Liu"
Alan King Lun LiuUniversity of Oxford Verified email at ndcn.ox.ac.uk Cited by 969 |
[HTML][HTML] Nucleus basalis of Meynert revisited: anatomy, history and differential involvement in Alzheimer's and Parkinson's disease
It has been well established that neuronal loss within the cholinergic nucleus basalis of
Meynert (nbM) correlates with cognitive decline in dementing disorders such as Alzheimer's …
Meynert (nbM) correlates with cognitive decline in dementing disorders such as Alzheimer's …
[HTML][HTML] Next generation histology methods for three-dimensional imaging of fresh and archival human brain tissues
Modern clearing techniques for the three-dimensional (3D) visualisation of neural tissue
microstructure have been very effective when used on rodent brain but very few studies …
microstructure have been very effective when used on rodent brain but very few studies …
Bringing CLARITY to the human brain: visualization of Lewy pathology in three dimensions
AKL Liu, MED Hurry, OTW Ng… - Neuropathology and …, 2016 - Wiley Online Library
Aims CLARITY is a novel technique which enables three‐dimensional visualization of
immunostained tissue for the study of circuitry and spatial interactions between cells and …
immunostained tissue for the study of circuitry and spatial interactions between cells and …
[HTML][HTML] Hippocampal CA2 Lewy pathology is associated with cholinergic degeneration in Parkinson's disease with cognitive decline
Although the precise neuropathological substrates of cognitive decline in Parkinson's
disease (PD) remain elusive, it has long been regarded that pathology in the CA2 …
disease (PD) remain elusive, it has long been regarded that pathology in the CA2 …
[HTML][HTML] Rationalisation and validation of an acrylamide-free procedure in three-dimensional histological imaging
Three-dimensional visualization of intact tissues is now being achieved by turning tissues
transparent. CLARITY is a unique tissue clearing technique, which features the use of …
transparent. CLARITY is a unique tissue clearing technique, which features the use of …
[HTML][HTML] ARTAG in the basal forebrain: widening the constellation of astrocytic tau pathology
AKL Liu, MH Goldfinger, HE Questari… - Acta Neuropathologica …, 2016 - Springer
ARTAG in the basal forebrain: widening the constellation of astrocytic tau pathology | Acta
Neuropathologica Communications Skip to main content SpringerLink Account Menu Find a …
Neuropathologica Communications Skip to main content SpringerLink Account Menu Find a …
[HTML][HTML] Prominent astrocytic alpha-synuclein pathology with unique post-translational modification signatures unveiled across Lewy body disorders
Alpha-synuclein (aSyn) is a pre-synaptic monomeric protein that can form aggregates in
neurons in Parkinson's disease (PD), Parkinson's disease with dementia (PDD) and …
neurons in Parkinson's disease (PD), Parkinson's disease with dementia (PDD) and …
Stem cell therapy for Alzheimer's disease: hype or hope?
AKL Liu - Bioscience Horizons, 2013 - academic.oup.com
Alzheimer's disease (AD) is the most common neurodegenerative disease affecting millions
of people in the world. Cognitive impairments such as progressive memory loss are …
of people in the world. Cognitive impairments such as progressive memory loss are …
Possible Contribution of Altered Cholinergic Activity in the Visual Cortex in Visual Hallucinations in Parkinson's Disease
L Sinclair, J Brenton, AKL Liu… - The Journal of …, 2022 - Am Neuropsych Assoc
Objective: Up to one-third of patients with Parkinson's disease (PD) experience visual
hallucinations (VHs). Lewy bodies are sparse in the visual cortices and seem unlikely to …
hallucinations (VHs). Lewy bodies are sparse in the visual cortices and seem unlikely to …
[HTML][HTML] Differential expression of galanin in the cholinergic basal forebrain of patients with Lewy body disorders
Introduction Depletion of cholinergic neurons within the nucleus basalis of Meynert (nbM) is
thought to contribute to the development of cognitive impairments in both Alzheimer's …
thought to contribute to the development of cognitive impairments in both Alzheimer's …