Pathological tau protein inclusions have long been recognized to define the diverse range of
neurodegenerative disorders called the tauopathies, which include Alzheimer's disease …

The clinical diagnosis of progressive supranuclear palsy (PSP) relies on the identification of
characteristic signs and symptoms. A proportion of pathologically diagnosed cases do not …

MATR3 is an RNA-and DNA-binding protein that interacts with TDP-43, a disease protein
linked to amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. Using exome …

To identify colorectal cancer (CRC) susceptibility alleles, we conducted a genome-wide
association study. In phase 1, we genotyped 550,163 tagSNPs in 940 familial colorectal …

To identify risk variants for colorectal cancer (CRC), we conducted a genome-wide
association study, genotyping 550,163 tag SNPs in 940 individuals with familial colorectal …

Two mutations in the DJ‐1 gene on chromosome1p36 have been identified recently to
cause early‐onset, autosomal recessive Parkinson's disease. As no information is available …

To elucidate the genetic architecture of amyotrophic lateral sclerosis (ALS) and find
associated loci, we assembled a custom imputation reference panel from whole-genome …

We conducted a genome-wide association study of 299,983 tagging SNPs for chronic
lymphocytic leukemia (CLL) and performed validation in two additional series totaling 1,529 …

Genome-wide association studies (GWAS) have identified ten loci harboring common
variants that influence risk of developing colorectal cancer (CRC). To enhance the power to …

Clinical syndromes associated with progressive supranuclear palsy-tau pathology now
include progressive supranuclear palsy-parkinsonism (PSP-P), in addition to classic …