Background Since the early 1980s, imaging techniques have enabled population-based
studies of intracerebral haemorrhage. We aimed to assess the incidence, case fatality, and …

Background and Purpose—The estimates on the prevalence and the risk of rupture of
intracranial saccular aneurysms vary widely between studies. We conducted a systematic …

Summary Background Unruptured intracranial aneurysms (UIAs) are increasingly detected
and are an important health-care burden. We aimed to assess the prevalence of UIAs …

Background Malignant infarction of the middle cerebral artery (MCA) is associated with an
80% mortality rate. Non-randomised studies have suggested that decompressive surgery …

Background High-dose aspirin (≥ 500 mg daily) reduces long-term incidence of colorectal
cancer, but adverse effects might limit its potential for long-term prevention. The long-term …

Background During the last three decades, new management strategies have been
developed for patients with aneurysmal subarachnoid hemorrhage. To assess whether the …

Background and aim: To update our 1996 review on the incidence of subarachnoid
haemorrhage (SAH) and assess the relation of incidence with region, age, gender and time …

Background In a systematic review, published in 1997, we found that the case fatality of
aneurysmal subarachnoid haemorrhage (SAH) decreased during the period 1960–95 …

Background The decision of whether to treat incidental intracranial saccular aneurysms is
complicated by limitations in current knowledge of their natural history. We combined …

Background The effects of pharmacological blood pressure lowering at normal or high-
normal blood pressure ranges in people with or without pre-existing cardiovascular disease …