Sporadic cerebral amyloid angiopathy revisited: recent insights into pathophysiology and clinical spectrum

A Charidimou, Q Gang, DJ Werring - Journal of Neurology …, 2012 - jnnp.bmj.com
Sporadic cerebral amyloid angiopathy (CAA) is a common age related cerebral small vessel
disease, characterised by progressive deposition of amyloid-β (Aβ) in the wall of small to …

Living systematic review: 1. Introduction—the why, what, when, and how

JH Elliott, A Synnot, T Turner, M Simmonds… - Journal of clinical …, 2017 - Elsevier
Systematic reviews are difficult to keep up to date, but failure to do so leads to a decay in
review currency, accuracy, and utility. We are developing a novel approach to systematic …

Emerging concepts in sporadic cerebral amyloid angiopathy

A Charidimou, G Boulouis, ME Gurol, C Ayata… - Brain, 2017 - academic.oup.com
Sporadic cerebral amyloid angiopathy is a common, well-defined small vessel disease and
a largely untreatable cause of intracerebral haemorrhage and contributor to age-related …

The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI–neuropathology diagnostic accuracy study

A Charidimou, G Boulouis, MP Frosch… - The Lancet …, 2022 - thelancet.com
Background Cerebral amyloid angiopathy (CAA) is an age-related small vessel disease,
characterised pathologically by progressive deposition of amyloid β in the cerebrovascular …

Diagnosis of cerebral amyloid angiopathy: evolution of the Boston criteria

SM Greenberg, A Charidimou - Stroke, 2018 - Am Heart Assoc
492 Stroke February 2018 lobar hemorrhages required for probable CAA, or alternatively
preclude probable CAA if in deep territories. The rationale for counting all types of …

Cortical superficial siderosis: detection and clinical significance in cerebral amyloid angiopathy and related conditions

A Charidimou, J Linn, MW Vernooij, C Opherk… - Brain, 2015 - academic.oup.com
Cortical superficial siderosis describes a distinct pattern of blood-breakdown product
deposition limited to cortical sulci over the convexities of the cerebral hemispheres, sparing …

[HTML][HTML] Living systematic reviews: 2. Combining human and machine effort

J Thomas, A Noel-Storr, I Marshall, B Wallace… - Journal of clinical …, 2017 - Elsevier
New approaches to evidence synthesis, which use human effort and machine automation in
mutually reinforcing ways, can enhance the feasibility and sustainability of living systematic …

Cerebral microbleeds and recurrent stroke risk: systematic review and meta-analysis of prospective ischemic stroke and transient ischemic attack cohorts

A Charidimou, P Kakar, Z Fox, DJ Werring - Stroke, 2013 - Am Heart Assoc
Background and Purpose—To evaluate cerebral microbleeds (CMBs) and future stroke risk
(including intracerebral hemorrhage [ICH]) in patients with ischemic stroke (IS) or transient …

Validation of clinicoradiological criteria for the diagnosis of cerebral amyloid angiopathy–related inflammation

E Auriel, A Charidimou, ME Gurol, J Ni… - JAMA …, 2016 - jamanetwork.com
Importance Cerebral amyloid angiopathy–related inflammation (CAA-ri) is an important
diagnosis to reach in clinical practice because many patients with the disease respond to …

Spectrum of transient focal neurological episodes in cerebral amyloid angiopathy: multicentre magnetic resonance imaging cohort study and meta-analysis

A Charidimou, A Peeters, Z Fox, SM Gregoire… - Stroke, 2012 - Am Heart Assoc
Background and Purpose—Transient focal neurological episodes (TFNE) are recognized in
cerebral amyloid angiopathy (CAA) and may herald a high risk of intracerebral hemorrhage …