Randomized trials have shown that selective serotonin reuptake inhibitors (SSRIs) and
serotonin-norepinephrine reuptake inhibitors (SNRIs) have better safety profiles than …

Dependence on tobacco, like many other drug dependencies, is a complex behavior with
both genetic and environmental factors contributing to the variance. The heritability …

The brain is an organ predisposed to oxidative/nitrosative stress. This is especially true in
the case of aging as well as several neurodegenerative diseases. Under such …

The precise mechanisms of pain perception and transmission in the central nervous system
have not been fully elucidated. However, extensive data support a role for the monoamine …

Background About 2% to 5% of all primary-care patients have a somatization disorder, and
somatic symptoms are strongly associated with comorbid depression and anxiety disorders …

Both the usage of prescription drugs such as opioid analgesics and benzodiazepines and
overdoses involving them have increased dramatically in the United States since the 1990s …

In an attempt to understand the reasons behind the high prevalence of tobacco smoking in
patients with schizophrenia, the study examined whether specific symptoms of …

BACKGROUND: We examined gender-specific prevalences, patterns, and correlates of non-
prescribed use of pain relievers–mainly opioids–in a representative sample of American …

We investigated whether measures of impulsivity, aggression and sensation seeking
differed between cocainedependent subjects and controls, and whether these measures …

We examined the efficacy and tolerability of augmentation with an extended release
formulation of methylphenidate (OROS MPH, Concerta) in patients with major depression …