Disability and cognitive impairment show similar patterns of increasing frequency with
ageing. A review of the published literature shows that there is a cross-sectional relationship …

Objective: To estimate the age-specific incidence rate of mild cognitive impairment (MCI)
according to sex and educational level and to explore the course of MCI, particularly its …

Better knowledge of the preclinical phase of Alzheimer's disease would be an important
advance to allow earlier treatment of this ominous disease. This prodromal period was …

Objective: To compare the power of tests assessing different cognitive domains for the
identification of prodromal Alzheimer disease (AD) among patients with mild cognitive …

Most of the social and economic burden of dementia is attributable to its consequences in
terms of disability. In this review, we describe the concepts defined in the disablement …

OBJECTIVE: To study the relationship between social and leisure activities and risk of
subsequent dementia in older community residents. SETTING: A cohort study of people …

Objectives: To establish the frequency of cognitive impairment in a population based sample
of patients with recently diagnosed relapsing-remitting multiple sclerosis (RRMS), and to …

✓ Obsessive—compulsive disorder (OCD) is an anxiety disorder associated with recurrent
intrusive thoughts and repetitive behaviors. Although conventional pharmacological and/or …

Objective: To describe the restriction in instrumental activities of daily living (IADL) in mild
cognitive impairment (MCI) and to assess the impact of IADL restriction on the progression to …

Objective: To analyze the relationship between marital status and risk of AD or dementia.
Methods: This study was carried out from the Personnes Agées QUID (PAQUID) cohort, an …