Schwannomas and their pathogenesis

DA Hilton, CO Hanemann - Brain pathology, 2014 - Wiley Online Library
Schwannomas may occur spontaneously, or in the context of a familial tumor syndrome such
as neurofibromatosis type 2 (NF 2), schwannomatosis and C arney's complex …

Causality in acute encephalitis: defining aetiologies

J Granerod, R Cunningham, M Zuckerman… - Epidemiology & …, 2010 - cambridge.org
Defining the causal relationship between a microbe and encephalitis is complex. Over 100
different infectious agents may cause encephalitis, often as one of the rarer manifestations of …

Creutzfeldt-Jakob disease: a systematic review of global incidence, prevalence, infectivity, and incubation

L Uttley, C Carroll, R Wong, DA Hilton… - The Lancet Infectious …, 2020 - thelancet.com
Creutzfeldt-Jakob disease (CJD) is a fatal disease presenting with rapidly progressive
dementia, and most patients die within a year of clinical onset. CJD poses a potential risk of …

Overexpression of hypoxia-inducible factor 1α in common human cancers and their metastases

H Zhong, AM De Marzo, E Laughner, M Lim, DA Hilton… - Cancer research, 1999 - AACR
Neovascularization and increased glycolysis, two universal characteristics of solid tumors,
represent adaptations to a hypoxic microenvironment that are correlated with tumor …

Prevalence of lymphoreticular prion protein accumulation in UK tissue samples

DA Hilton, AC Ghani, L Conyers… - The Journal of …, 2004 - Wiley Online Library
This study aims to provide an estimate of the number of individuals in the UK who may be
incubating variant Creutzfeldt‐Jakob disease and at risk of causing iatrogenic spread of the …

Aβ-related angiitis: primary angiitis of the central nervous system associated with cerebral amyloid angiopathy

NJ Scolding, F Joseph, PA Kirby, I Mazanti, F Gray… - Brain, 2005 - academic.oup.com
Idiopathic or primary angiitis of the CNS (PACNS) and cerebral amyloid angiopathy (CAA)
are unusual vasculopathies generally regarded as unrelated disorders. A few case reports …

Prevalent abnormal prion protein in human appendixes after bovine spongiform encephalopathy epizootic: large scale survey

ON Gill, Y Spencer, A Richard-Loendt, C Kelly… - Bmj, 2013 - bmj.com
Objectives To carry out a further survey of archived appendix samples to understand better
the differences between existing estimates of the prevalence of subclinical infection with …

Prion immunoreactivity in appendix before clinical onset of variant Creutzfeldt-Jakob disease

DA Hilton, E Fathers, P Edwards, JW Ironside, J Zajicek - The Lancet, 1998 - thelancet.com
Low-power view of appendix after immunocytochemistry for PrP (A) and high-power view of
germinal centre after double labelling for PrP and CD21 (B) Scattered cytoplasmic PrP …

Mutations in TTBK2, encoding a kinase implicated in tau phosphorylation, segregate with spinocerebellar ataxia type 11

H Houlden, J Johnson, C Gardner-Thorpe, T Lashley… - Nature …, 2007 - nature.com
The microtubule-associated protein tau (encoded by MAPT) and several tau kinases have
been implicated in neurodegeneration, but only MAPT has a proven role in disease. We …

Pathological findings associated with trigeminal neuralgia caused by vascular compression

DA Hilton, S Love, T Gradidge, HB Coakham - Neurosurgery, 1994 - journals.lww.com
Abstract VASCULAR COMPRESSION OF the trigeminal nerve root accounts for more than
80% of intractable cases of trigeminal neuralgia, but the pathogenesis is still debated. The …