Recent advances in single-cell RNA sequencing technologies enable deep insights into
cellular development, gene regulation, and phenotypic diversity by measuring gene …

Quantitative views of cellular functions require precise measures of rates of biomolecule
production, especially proteins—the direct effectors of biological processes. Here, we …

Objective To investigate the role of matrix metalloproteinase 13 (MMP‐13; collagenase 3) in
osteoarthritis (OA). Methods OA was surgically induced in the knees of MMP‐13–knockout …

The high-dimensional data created by high-throughput technologies require visualization
tools that reveal data structure and patterns in an intuitive form. We present PHATE, a …

Objectives: We aimed to determine the safety and efficacy of pulmonary vein isolation (PVI)
in atrial fibrillation (AF) patients with impaired left ventricular (LV) systolic function …

Objectives: This study investigated the impact on recurrences of 2 different substrate
approaches for the treatment of these arrhythmias. Background: Catheter ablation of …

Objectives: The aim of this multicenter study was to evaluate the safety of discontinuing oral
anticoagulation therapy (OAT) after apparently successful pulmonary vein isolation …

Objective The relationship between the topographical variations in the structural,
biochemical and dynamic biomechanical properties of articular cartilage (AC) before and 6 …

Background—Left atrioesophageal fistula is a rare but devastating complication that may
occur after catheter ablation of atrial fibrillation. We used capsule endoscopy to assess …

Hemiptera, the largest non-holometabolous order of insects, represents approximately 7% of
metazoan diversity. With extraordinary life histories and highly specialized morphological …