User profiles for "author:D Devos"

David DEVOS

- Verified email at chru-lille.fr - Cited by 14687

Damien P Devos

- Verified email at pasteur-lille.fr - Cited by 10109

Colonic inflammation in Parkinson's disease

D Devos, T Lebouvier, B Lardeux, M Biraud… - Neurobiology of …, 2013 - Elsevier
Lewy pathology affects the gastrointestinal tract in Parkinson's disease (PD) and data from
recent genetic studies suggest a link between PD and gut inflammation. We therefore …

Ferroptosis and its potential role in the physiopathology of Parkinson's Disease

…, H Bouchaoui, S Ayton, D Devos… - Progress in …, 2021 - Elsevier
Parkinson's Disease (PD) is a common and progressive neurodegenerative disorder
characterised by motor impairments as well as non-motor symptoms. While dopamine …

Striking while the iron is hot: Iron metabolism and ferroptosis in neurodegeneration

S Masaldan, AI Bush, D Devos, AS Rolland… - Free Radical Biology …, 2019 - Elsevier
Perturbations in iron homeostasis and iron accumulation feature in several
neurodegenerative disorders including Alzheimer's disease (AD), Parkinson's disease (PD) …

The molecular architecture of the nuclear pore complex

…, LM Veenhoff, W Zhang, J Kipper, D Devos… - Nature, 2007 - nature.com
Nuclear pore complexes (NPCs) are proteinaceous assemblies of approximately 50 MDa
that selectively transport cargoes across the nuclear envelope. To determine the molecular …

Targeting chelatable iron as a therapeutic modality in Parkinson's disease

D Devos, C Moreau, JC Devedjian, J Kluza… - Antioxidants & redox …, 2014 - liebertpub.com
Aims: The pathophysiological role of iron in Parkinson's disease (PD) was assessed by a
chelation strategy aimed at reducing oxidative damage associated with regional iron …

[HTML][HTML] Trial of deferiprone in Parkinson's disease

D Devos, J Labreuche, O Rascol… - … England Journal of …, 2022 - Mass Medical Soc
Background Iron content is increased in the substantia nigra of persons with Parkinson's
disease and may contribute to the pathophysiology of the disorder. Early research suggests …

Proteome organization in a genome-reduced bacterium

…, D Castaño-Diez, WH Chen, D Devos… - Science, 2009 - science.org
The genome of Mycoplasma pneumoniae is among the smallest found in self-replicating
organisms. To study the basic principles of bacterial proteome organization, we used …

Prediction of human protein function from post-translational modifications and localization features

LJ Jensen, R Gupta, N Blom, D Devos… - Journal of molecular …, 2002 - Elsevier
We have developed an entirely sequence-based method that identifies and integrates
relevant features that can be used to assign proteins of unknown function to functional …

Determining the architectures of macromolecular assemblies

…, LM Veenhoff, W Zhang, J Kipper, D Devos… - Nature, 2007 - nature.com
To understand the workings of a living cell, we need to know the architectures of its
macromolecular assemblies. Here we show how proteomic data can be used to determine …

Practical limits of function prediction

D Devos, A Valencia - Proteins: Structure, Function, and …, 2000 - Wiley Online Library
The widening gap between known protein sequences and their functions has led to the
practice of assigning a potential function to a protein on the basis of sequence similarity to …