Telemedicine in neurology: telemedicine work group of the American Academy of Neurology update

…, M Dolan O'Brien, DS Eliashiv, D Erten-Lyons… - Neurology, 2020 - AAN Enterprises
Purpose While there is strong evidence supporting the importance of telemedicine in stroke,
its role in other areas of neurology is not as clear. The goal of this review is to provide an …

Neuropathologic basis of white matter hyperintensity accumulation with advanced age

D Erten-Lyons, R Woltjer, J Kaye, N Mattek, HH Dodge… - Neurology, 2013 - AAN Enterprises
Objective: To determine which vascular pathology measure most strongly correlates with
white matter hyperintensity (WMH) accumulation over time, and whether Alzheimer disease …

[HTML][HTML] Trial of pimavanserin in dementia-related psychosis

…, C Ballard, D Erten-Lyons… - … England Journal of …, 2021 - Mass Medical Soc
Background Patients with dementia due to neurodegenerative disease can have dementia-
related psychosis. The effects of the oral 5-HT2A inverse agonist and antagonist …

Factors associated with resistance to dementia despite high Alzheimer disease pathology

D Erten-Lyons, RL Woltjer, H Dodge, R Nixon… - Neurology, 2009 - AAN Enterprises
Background: Autopsy series have shown that some elderly people remain with normal
cognitive function during life despite having high burdens of pathologic lesions associated …

Neuropathologic basis of age-associated brain atrophy

D Erten-Lyons, HH Dodge, R Woltjer, LC Silbert… - JAMA …, 2013 - jamanetwork.com
Importance While brain volume changes are used as surrogate markers for Alzheimer
disease neuropathology in clinical studies, the extent to which these changes are due to …

[HTML][HTML] Characterizing the white matter hyperintensity penumbra with cerebral blood flow measures

…, D Lahna, JA Kaye, HH Dodge, D Erten-Lyons… - NeuroImage: Clinical, 2015 - Elsevier
Abstract Objective White matter hyperintensities (WMHs) are common with age, grow over
time, and are associated with cognitive and motor impairments. Mechanisms underlying …

Trajectory of white matter hyperintensity burden preceding mild cognitive impairment

…, LG Perkins, L Sherbakov, D Lahna, D Erten-Lyons… - Neurology, 2012 - AAN Enterprises
Objective: To determine the time of acceleration in white matter hyperintensity (WMH)
burden, a common indicator of cerebrovascular pathology, in relation to conversion to mild …

Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study

…, RL Woltjer, SK Westaway, D Clark, D Erten-Lyons… - Neurobiology of …, 2011 - Elsevier
Many elderly individuals remain dementia-free throughout their life. However, some of these
individuals exhibit Alzheimer disease neuropathology on autopsy, evidenced by …

[HTML][HTML] The effects of noncoding aquaporin-4 single-nucleotide polymorphisms on cognition and functional progression of Alzheimer's disease

…, SK Westaway, MJ Simon, D Erten-Lyons… - Alzheimer's & Dementia …, 2017 - Elsevier
Introduction The glymphatic system is a brain-wide perivascular network that facilitates
clearance of proteins, including amyloid β, from the brain interstitium through the …

Dementia care comes home: patient and caregiver assessment via telemedicine

…, N Mattek, K Mincks, J Kaye, D Erten-Lyons - The …, 2017 - academic.oup.com
Abstract Purpose of the Study We evaluated the feasibility and reliability of commonly used
clinical dementia assessments when administered via direct-to-home telemedicine …