User profiles for "author:D Smith"

David A Smith

- Verified email at uci.edu - Cited by 54877

Derek J Smith

- Verified email at cam.ac.uk - Cited by 23062

Status and ecological effects of the world's largest carnivores

WJ Ripple, JA Estes, RL Beschta, CC Wilmers… - Science, 2014 - science.org
Background The largest terrestrial species in the order Carnivora are wide-ranging and rare
because of their positions at the top of food webs. They are some of the world's most …

Metamaterials and negative refractive index

DR Smith, JB Pendry, MCK Wiltshire - science, 2004 - science.org
Recently, artificially constructed metamaterials have become of considerable interest,
because these materials can exhibit electromagnetic characteristics unlike those of any …

Analysis of the structural diversity, substitution patterns, and frequency of nitrogen heterocycles among US FDA approved pharmaceuticals: miniperspective

E Vitaku, DT Smith, JT Njardarson - Journal of medicinal chemistry, 2014 - ACS Publications
Nitrogen heterocycles are among the most significant structural components of
pharmaceuticals. Analysis of our database of US FDA approved drugs reveals that 59% of …

GEANT4—a simulation toolkit

…, S Scherer, S Sei, V Sirotenko, D Smith… - Nuclear instruments and …, 2003 - Elsevier
Geant4 is a toolkit for simulating the passage of particles through matter. It includes a
complete range of functionality including tracking, geometry, physics models and hits. The …

Experimental observation of isolated large transverse energy electrons with associated missing energy at s= 540 GeV

…, M Spiro, J Strauss, K Sumorok, F Szoncso, D Smith… - Physics Letters B, 1983 - Elsevier
We report the results of two searches made on data recorded at the CERN SPS Proton-
Antiproton Collider: one for isolated large-ET electrons, the other for large-ET neutrinos …

Experimental observation of lepton pairs of invariant mass around 95 GeV/c2 at the CERN SPS collider

…, J Strauss, J Streets, K Sumorok, F Szoncso, D Smith… - Physics letters B, 1983 - Elsevier
We report the observation of four electron-positron pairs and one muon pair which have the
signature of a two-body decay of a particle of mass∼ 95 GeV/c2. These events fit well the …

[HTML][HTML] Safety, activity, and immune correlates of anti–PD-1 antibody in cancer

SL Topalian, FS Hodi, JR Brahmer… - … England Journal of …, 2012 - Mass Medical Soc
Background Blockade of programmed death 1 (PD-1), an inhibitory receptor expressed by T
cells, can overcome immune resistance. We assessed the antitumor activity and safety of …

K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification

…, G Payne, RA Rivera-Mizzoni, D Smith… - American Journal of …, 2002 - jhu.pure.elsevier.com
Introduction: Chronic kidney disease as a public health problem. Chronic kidney disease is
a worldwide public health problem. In the United States, there is a rising incidence and …

Geant4 developments and applications

…, S Sadilov, G Santin, T Sasaki, D Smith… - … on nuclear science, 2006 - ieeexplore.ieee.org
Geant4 is a software toolkit for the simulation of the passage of particles through matter. It is
used by a large number of experiments and projects in a variety of application domains …

An integrated genomic analysis of human glioblastoma multiforme

DW Parsons, S Jones, X Zhang, JCH Lin, RJ Leary… - science, 2008 - science.org
Glioblastoma multiforme (GBM) is the most common and lethal type of brain cancer. To
identify the genetic alterations in GBMs, we sequenced 20,661 protein coding genes …