Free radicals are highly reactive chemical species generated during normal metabolic
processes, which in excess can lead to membrane damage. Elaborate anti-oxidant defence …

It is generally believed that treatments are available to manage chorea in Huntington's
disease (HD). However, lack of evidence prevents the establishment of treatment guidelines …

A role for γ-aminobutyric acid (GABA) in the pathophysiology of schizophrenia was first
suggested by Eugene Roberts in 1972. Since then considerable work has been …

• Local cerebral uptake of deoxyglucose labeled with fluorine 18 was measured by positron-
emission tomography in eight patients with schizophrenia who were not receiving …

Background: Abrupt discontinuation of long-term psychotropic medication can be followed
by a high risk of early relapse. This study aimed to quantify the relapse risk over time in …

To examine whether antioxidant capacity is reduced in patients with schizophrenia, we
determined plasma total antioxidant status (TAS) by quenching the absorbance of the …

Background: The hypothesis that exposure to traumatic events may sensitize or kindle limbic
nuclei has led to efforts to treat posttraumatic stress disorder (PTSD) with anticonvulsants …

On the basis of a review of the literature describing the process of schizophrenic illness, the
authors conclude that schizophrenic psychosis is one stage in a process of psychological …

Social cognition has received increasing attention in schizophrenia due to its theoretical
relevance to core features of the disorder as well as the marked deficits in social functioning …

Sertindole is a novel antipsychotic agent with high selectivity for the mesolimbic
dopaminergic pathway and nanomolar affinities for dopamine D 2, serotonin 5-HT 2, and …