Updated meta‐analysis of classical fear conditioning in the anxiety disorders

P Duits, DC Cath, S Lissek, JJ Hox… - Depression and …, 2015 - Wiley Online Library
The aim of the current study was twofold:(1) to systematically examine differences in fear
conditioning between anxiety patients and healthy controls using meta‐analytic methods …

Twin studies on obsessive–compulsive disorder: a review

DS Van Grootheest, DC Cath, AT Beekman… - Twin Research and …, 2005 - cambridge.org
Genetic factors have historically been thought of as important in the development of
obsessive–compulsive disorder (OCD). For the estimation of the relative importance of …

Patient selection and assessment recommendations for deep brain stimulation in Tourette syndrome

JW Mink, J Walkup, KA Frey, P Como… - … : official journal of the …, 2006 - Wiley Online Library
In response to recent publicity regarding the potential use of deep brain stimulation (DBS)
for reducing tic severity in Tourette's syndrome (TS), the Tourette Syndrome Association …

[HTML][HTML] Factor structure, reliability and criterion validity of the Autism-Spectrum Quotient (AQ): a study in Dutch population and patient groups

RA Hoekstra, M Bartels, DC Cath… - Journal of autism and …, 2008 - Springer
The factor structure of the Dutch translation of the Autism-Spectrum Quotient (AQ; a
continuous, quantitative measure of autistic traits) was evaluated with confirmatory factor …

Lifetime prevalence, age of risk, and genetic relationships of comorbid psychiatric disorders in Tourette syndrome

ME Hirschtritt, PC Lee, DL Pauls, Y Dion… - JAMA …, 2015 - jamanetwork.com
Importance Tourette syndrome (TS) is characterized by high rates of psychiatric comorbidity;
however, few studies have fully characterized these comorbidities. Furthermore, most …

Frontal-striatal dysfunction during planning in obsessive-compulsive disorder

OA Van Den Heuvel, DJ Veltman… - Archives of general …, 2005 - jamanetwork.com
Background Dysfunction of frontal-striatal, particularly orbitofrontal-striatal, circuitry has been
implicated in the pathophysiology of obsessive-compulsive disorder (OCD), characterized …

Disorder-specific neuroanatomical correlates of attentional bias in obsessive-compulsive disorder, panic disorder, and hypochondriasis

OA Van den Heuvel, DJ Veltman… - Archives of general …, 2005 - jamanetwork.com
Context Attentional bias to disease-relevant emotional cues is considered to be
pathogenetically relevant in anxiety disorders. Objective To investigate functional neural …

Reduced orbitofrontal-striatal activity on a reversal learning task in obsessive-compulsive disorder

PL Remijnse, MMA Nielen… - Archives of general …, 2006 - jamanetwork.com
Context The orbitofrontal cortex (OFC)–striatal circuit, which is important for motivational
behavior, is assumed to be involved in the pathophysiology of obsessive-compulsive …

Genome-wide association study of obsessive-compulsive disorder

SE Stewart, D Yu, JM Scharf, BM Neale… - Molecular …, 2013 - nature.com
Obsessive-compulsive disorder (OCD) is a common, debilitating neuropsychiatric illness
with complex genetic etiology. The International OCD Foundation Genetics Collaborative …

[HTML][HTML] Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture

LK Davis, D Yu, CL Keenan, ER Gamazon… - PLoS …, 2013 - journals.plos.org
The direct estimation of heritability from genome-wide common variant data as implemented
in the program Genome-wide Complex Trait Analysis (GCTA) has provided a means to …