1 Purpose These reporting guidelines are intended to facilitate analysis and reporting of
clinical results of various therapeutic approaches to diseased heart valves such that …

Over the last 10–15 years, our understanding of the composition and functions of the human
gut microbiota has increased exponentially. To a large extent, this has been due to new …

Since the introduction of insulin almost a century ago, more than 80 peptide drugs have
reached the market for a wide range of diseases, including diabetes, cancer, osteoporosis …

Background We compared transcatheter aortic-valve replacement (TAVR), using a self-
expanding transcatheter aortic-valve bioprosthesis, with surgical aortic-valve replacement in …

Background Baricitinib is an oral selective Janus kinase 1/2 inhibitor with known anti-
inflammatory properties. This study evaluates the efficacy and safety of baricitinib in …

Background Transcatheter aortic-valve replacement (TAVR) is an alternative to surgery in
patients with severe aortic stenosis who are at increased risk for death from surgery; less is …

In retrospect it is not surprising that reformers should look to schools as central to the
solution of the Indian problem. As an instrument for fostering social cohesion and …

Background Although transcatheter aortic-valve replacement (TAVR) is an accepted
alternative to surgery in patients with severe aortic stenosis who are at high surgical risk …

Abstract ALZHEIMER'S disease (AD) is the most common cause of progressive intellectual
failure in aged humans. AD brains contain numerous amyloid plaques surrounded by …

Background Atrial fibrillation (AF) after coronary artery bypass surgery (CABG) is the most
common sustained arrhythmia. Its pathophysiology is unclear, and its prevention and …