Postural orthostatic tachycardia syndrome: the Mayo clinic experience

MJ Thieben, P Sandroni, DM Sletten… - Mayo Clinic …, 2007 - Elsevier
OBJECTIVE To evaluate the prevalence and pathogenetic mechanisms of postural
orthostatic tachycardia syndrome (POTS). PATIENTS AND METHODS We reviewed the …

Autonomic symptoms and diabetic neuropathy: a population-based study

PA Low, LM Benrud-Larson, DM Sletten… - Diabetes …, 2004 - Am Diabetes Assoc
OBJECTIVE—The prevalence of autonomic symptoms and deficits in certain systems is
known, but a comprehensive autonomic symptom profile in diabetes is not available. We …

COMPASS 31: a refined and abbreviated Composite Autonomic Symptom Score

DM Sletten, GA Suarez, PA Low, J Mandrekar… - Mayo Clinic …, 2012 - Elsevier
Objective To develop a concise and statistically robust instrument to assess autonomic
symptoms that provides clinically relevant scores of autonomic symptom severity based on …

Natural history of multiple system atrophy in the USA: a prospective cohort study

PA Low, SG Reich, J Jankovic, CW Shults… - The Lancet …, 2015 - thelancet.com
Background Multiple system atrophy is a rare, fatal neurodegenerative disorder with
symptoms of autonomic failure plus parkinsonism, cerebellar ataxia, or both. We report …

Postural tachycardia in children and adolescents: what is abnormal?

W Singer, DM Sletten, TL Opfer-Gehrking… - The Journal of …, 2012 - Elsevier
OBJECTIVES: To evaluate whether the use of adult heart rate (HR) criteria is appropriate for
diagnosing orthostatic intolerance (OI) and postural tachycardia syndrome (POTS) in …

Prospective differentiation of multiple system atrophy from Parkinson disease, with and without autonomic failure

A Lipp, P Sandroni, JE Ahlskog, RD Fealey… - Archives of …, 2009 - jamanetwork.com
Objective To report preliminary results of a prospective ongoing study of multiple system
atrophy (MSA) and Parkinson disease (PD), with a large subset of patients with PD with …

Clinical features and autonomic testing predict survival in multiple system atrophy

EA Coon, DM Sletten, MD Suarez, JN Mandrekar… - Brain, 2015 - academic.oup.com
Abstract See Colosimo and Berardelli (doi: 10.1093/brain/awv303) for a scientific
commentary on this article. Multiple system atrophy is characterized by autonomic failure …

Alpha‐synuclein oligomers and neurofilament light chain in spinal fluid differentiate multiple system atrophy from Lewy body synucleinopathies

W Singer, AM Schmeichel, M Shahnawaz… - Annals of …, 2020 - Wiley Online Library
Objective To explore the role of alpha‐synuclein (αSyn) oligomers and neurofilament light
chain (NFL) in cerebrospinal fluid (CSF) as markers of early multiple system atrophy (MSA) …

Alpha‐Synuclein oligomers and Neurofilament light chain predict Phenoconversion of pure autonomic failure

W Singer, AM Schmeichel, M Shahnawaz… - Annals of …, 2021 - Wiley Online Library
Objective To explore the role of alpha‐synuclein (αSyn) oligomers and neurofilament light
chain (NfL) in cerebrospinal fluid (CSF) of patients with pure autonomic failure (PAF) as …

Autopsy confirmed multiple system atrophy cases: Mayo experience and role of autonomic function tests

V Iodice, A Lipp, JE Ahlskog, P Sandroni… - Journal of Neurology …, 2012 - jnnp.bmj.com
Background Multiple system atrophy (MSA) is a sporadic progressive neurodegenerative
disorder characterised by autonomic failure, manifested as orthostatic hypotension or …