Background Valproate is widely accepted as a drug of first choice for patients with
generalised onset seizures, and its broad spectrum of efficacy means it is recommended for …

Background Carbamazepine is widely accepted as a drug of first choice for patients with
partial onset seizures. Several newer drugs possess efficacy against these seizure types but …

As part of a large community‐based study, we retrospectively examined the clinical course
of epilepsy in an unselected population of people who had a recent history of seizures or …

This paper describes the output of the PERMIS project, which has developed a role based
access control infrastructure that uses X. 509 attribute certificates (ACs) to store the users' …

Background Carbamazepine and valproate are drugs of first choice for epilepsy. Despite the
lack of hard evidence from individual randomized controlled trials, there is strong clinical …

Purpose: This randomised, double‐blind study compared the newer antiepileptic drugs
(AEDs) gabapentin (GBP) and lamotrigine (LTG) as monotherapy in newly diagnosed …

Purpose: The increased risk of mortality among people with epilepsy is well documented;
people with epilepsy are more likely than the general population to die as a result of an …

Summary Background The MRC Multicentre trial for Early Epilepsy and Single Seizures
(MESS) showed a reduced risk of further seizures in patients, for whom treatment with …

Background: A strong pharmacogenetic association has been reported in Chinese patients
between human leukocyte antigen (HLA)-B* 1502 and carbamazepine (CBZ)-induced …

Purpose: To provide an overview of the evidence comparing carbamazepine (CBZ) and
valproate (VPA) monotherapy for epilepsy, investigating whether existing data support the …