Brain atrophy and disability progression in multiple sclerosis patients: a 10-year follow-up study

C Jacobsen, J Hagemeier, KM Myhr… - Journal of Neurology …, 2014 - jnnp.bmj.com
Objectives To identify MRI biomarkers associated with long-term disability progression in
patients with multiple sclerosis (MS), and to define the rate of evolution of global, tissue …

Cardiovascular risk factors are associated with increased lesion burden and brain atrophy in multiple sclerosis

N Kappus, B Weinstock-Guttman… - Journal of Neurology …, 2016 - jnnp.bmj.com
Background Cardiovascular (CV) risk factors have been associated with changes in clinical
outcomes in patients with multiple sclerosis (MS). Objectives To investigate the frequency of …

The place of conventional MRI and newly emerging MRI techniques in monitoring different aspects of treatment outcome

R Zivadinov, M Stosic, JL Cox, DP Ramasamy… - Journal of …, 2008 - Springer
Magnetic resonance imaging (MRI) is the most important paraclinical measure for assessing
and monitoring the pathologic changes implicated in the onset and progression of multiple …

Leptomeningeal contrast enhancement is associated with progression of cortical atrophy in MS: a retrospective, pilot, observational longitudinal study

R Zivadinov, DP Ramasamy… - Multiple Sclerosis …, 2017 - journals.sagepub.com
Background: Leptomeningeal contrast enhancement (LM CE) has been recently described
in multiple sclerosis (MS) patients as a potential in vivo marker of cortical pathology …

A serial 10-year follow-up study of brain atrophy and disability progression in RRMS patients

R Zivadinov, T Uher, J Hagemeier… - Multiple Sclerosis …, 2016 - journals.sagepub.com
Background: We explored the evolution of brain atrophy in relation to development of
confirmed disability progression (CDP) on serial 1.5 T magnetic resonance imaging (MRI) …

Cognitive reserve moderates the impact of subcortical gray matter atrophy on neuropsychological status in multiple sclerosis

CM Modica, N Bergsland, MG Dwyer… - Multiple Sclerosis …, 2016 - journals.sagepub.com
Background: Cognitive decline is characterized in multiple sclerosis (MS), but the rate and
severity vary. The reserve hypothesis proposes that baseline neurological differences …

Cerebral microbleeds in multiple sclerosis evaluated on susceptibility-weighted images and quantitative susceptibility maps: a case-control study

R Zivadinov, DP Ramasamy, RRH Benedict, P Polak… - Radiology, 2016 - pubs.rsna.org
Purpose To assess cerebral microbleed (CMB) prevalence in patients with multiple sclerosis
(MS) and clinically isolated syndrome (CIS) and associations with clinical outcomes …

Jugular venous reflux and white matter abnormalities in Alzheimer's disease: a pilot study

CP Chung, C Beggs, PN Wang… - Journal of …, 2014 - content.iospress.com
To determine whether jugular venous reflux (JVR) is associated with cerebral white matter
changes (WMCs) in individuals with Alzheimer's disease (AD), we studied 12 AD patients 24 …

Atrophied brain lesion volume: a new imaging biomarker in multiple sclerosis

MG Dwyer, N Bergsland, DP Ramasamy… - Journal of …, 2018 - Wiley Online Library
ABSTRACT BACKGROUND AND PURPOSE Lesion accrual in multiple sclerosis (MS) is an
important and clinically relevant measure, used extensively as an imaging trial endpoint …

Atrophied brain T2 lesion volume at MRI is associated with disability progression and conversion to secondary progressive multiple sclerosis

AV Genovese, J Hagemeier, N Bergsland… - Radiology, 2019 - pubs.rsna.org
Background Atrophied T2 lesion volume at MRI is an imaging measure that reflects the
replacement of T2 lesions by cerebrospinal fluid spaces in patients with multiple sclerosis …