Therapeutic delivery of proteins to macrophages: implications for treatment of Gaucher's disease

PK Mistry, EP Wraight, TM Cox - The Lancet, 1996 - thelancet.com
Background The primary defect in Gaucher's disease, a lysosomal disorder affecting
macrophages, is in the activity of glucocerebrosidase. Treatment with exogenous enzyme …

Neuropsychological and SPECT scan findings during and after transient global amnesia: evidence for the differential impairment of remote episodic memory.

J Evans, B Wilson, EP Wraight… - Journal of Neurology …, 1993 - jnnp.bmj.com
A patient had neuropsychological testing during, and at two days and seven weeks after a
transient global amnesia (TGA) attack. During the attack she exhibited a characteristically …

Accuracy of serology for the diagnosis of Helicobacter pylori infection--a comparison of eight kits.

MH Wilcox, TH Dent, JO Hunter, JJ Gray… - Journal of clinical …, 1996 - jcp.bmj.com
AIMS: To determine the accuracy of eight commercially available kits for the serological
diagnosis of Helicobacter pylori infection, and hence whether a serology service could be …

In vivo studies of amylose-and ethylcellulose-coated [13C] glucose microspheres as a model for drug delivery to the colon

JH Cummings, S Milojevic, M Harding… - Journal of controlled …, 1996 - Elsevier
The observation that certain starches naturally present in the diet resist pancreatic enzymes
and reach the colon where they are fermented by bacterial amylases has been exploited to …

Cerebral vasculitis—recognition, diagnosis and management

NJ Scolding, DRW Jayne, JP Zajicek… - … Journal of Medicine, 1997 - academic.oup.com
Cerebral vasculitis is a serious but uncommon condition which presents considerable
difficulties in recognition, diagnosis and treatment. We studied eight consecutive patients in …

Leg muscle scintigraphy with 99Tcm-MIBI in the assessment of peripheral vascular (arterial) disease

KA Miles, RW Barber, EP Wraight… - Nuclear medicine …, 1992 - journals.lww.com
A technique for using 99 Tc m-methoxyisobutylisonitrile (MIBI) to evaluate leg muscle
perfusion in the assessment of peripheral vascular disease (PVD) is described and …

The value of technetium and gallium scanning in assessing pain after total hip replacement

N Rushton, AJ Coakley, J Tudor… - The Journal of Bone & …, 1982 - boneandjoint.org.uk
MATERIALS AND METHODS Fifty-one patients presenting at Addenbrooke's Hospital with
pain in the hip after total replacement were studied using radioisotope scanning. Patients …

The use of a chelating derivative of alpha melanocyte stimulating hormone for the clinical imaging of malignant melanoma

EP Wraight, DR Bard, TS Maughan… - The British Journal of …, 1992 - birpublications.org
A novel chelating derivative of alpha melanocyte stimulating hormone, bisMSH-DTPA, has
been used for the diagnostic targeting of malignant melanoma. 15 patients were …

Role of lacrimal scintigraphy and subtraction macrodacryocystography in the management of epiphora.

LA Amanat, EP Wraight, PG Watson… - British Journal of …, 1979 - bjo.bmj.com
Fifty-one patients were investigated by subtraction macrodacryocystography (SMDCG, 103
systems) and by lacrimal scintigraphy (LS, 105 systems). It was found that these …

Liver scan abnormalities in polymyalgia rheumatica/giant cell arteritis

V Kyle, EP Wraight, BL Hazleman - Clinical rheumatology, 1991 - Springer
Liver involvement in polymyalgia rheumatica/giant cell arteritis (PMR/GCA) before treatment
and during follow-up of up to 3 1/2 years was assessed in 74 patients clinically, with liver …