Objective In multiple sclerosis (MS), MRI measures at the whole brain or regional level are
only modestly associated with disability, while network-based measures are emerging as …

Clinical, pathological, and imaging evidence in multiple sclerosis (MS) suggests that a
smoldering inflammatory activity is present from the earliest stages of the disease and …

Background Network-based measures are emerging MRI markers in multiple sclerosis (MS).
We aimed to identify networks of white (WM) and grey matter (GM) damage that predict …

Objective The purpose of this study was to evaluate the extent to which treatment effect on
magnetic resonance imaging (MRI)‐derived measures of brain atrophy and focal lesions …

Objective Resting-state functional magnetic resonance imaging (fMRI) is promising for
Alzheimer's disease (AD). This study aimed to examine short-term reliability of the default …

Background: In Alzheimer's disease (AD), the abnormal aggregation of
hyperphosphorylated tau leads to synaptic dysfunction and neurodegeneration. Recently …

My work, presented in this thesis, aimed to define MRI markers to be used in clinical trials for
identifying participants most likely to worsen, monitoring disease progression, and …

Disentangling brain ageing from disease-related neurodegeneration in patients with
multiple sclerosis (PwMS) is increasingly topical. The brain-age paradigm offers a window …

Objective In multiple sclerosis (MS), magnetic resonance imaging (MRI) measures at the
whole brain or regional level are only modestly associated with disability, while network …

Disruptions to brain networks, measured using either structural (sMRI), diffusion (dMRI), or
resting-state functional (rs-fMRI) MRI, have been shown in people with multiple sclerosis …