T cell homing to peripheral lymph nodes (PLNs) is defined by a multistep sequence of
interactions between lymphocytes and endothelial cells in high endothelial venules (HEVs) …

Noninflamed skin venules support constitutive leukocyte rolling. P-selectin controls the
rolling frequency, whereas E-selectin dictates rolling velocity (V roll). Fucosylated selectin …

We purified CALLA from human kidney and isolated a cDNA clone reactive with two
oligonucleotide probes corresponding to two distinct peptides. The amino acid sequence …

A class of 3, 5-diphenyl-1, 2, 4-oxadiazole based compounds have been identified as potent
sphingosine-1-phosphate-1 (S1P1) receptor agonists with minimal affinity for the S1P2 and …

Abstract FTY720 (2-amino-[2-(4-octylphenyl) ethyl]-1, 3-propanediol hydrochloride) is an
immunosuppressive agent that inhibits allograft rejection. We recently demonstrated that …

Abstract The sphingosine-1-phosphate (S1P) receptor agonist, phosphorylated FTY720
(FTY-P), causes lymphopenia, lymphocyte sequestration in mesenteric lymph nodes …

Nonirradiated bone marrow (BM) venules and sinusoids in murine skull support
hematopoietic progenitor cell (HPC) rolling through constitutively expressed endothelial (P …

In adult mammals, leukocyte recruitment follows a well-defined cascade of adhesion events
enabling leukocytes to leave the circulatory system and transmigrate into tissue. Currently, it …

Lymphocytes home to peripheral lymph nodes (PLNs) via high endothelial venules (HEVs)
in the subcortex and incrementally larger collecting venules in the medulla. HEVs express …

The reactivity of a panel of monoclonal antibodies (MAb) produced against non-T, non-B
acute lymphoblastic leukemia cells was investigated by immunoperoxidase staining of …