Using a philosophical approach or deductive reasoning, we challenge the dominant clinico-
radiological worldview that defines multiple sclerosis (MS) as a focal inflammatory disease …

Graft versus host disease (GvHD) is the clinical condition in which bone marrow-derived
mesenchymal stromal cells (MSCs) have been most frequently studied. In this review, we …

While the major phenotypes of multiple sclerosis (MS) and relapsing–remitting, primary and
secondary progressive MS have been well characterized, a subgroup of patients with an …

Multiple sclerosis is a chronic, often disabling, disease of the central nervous system
affecting more than 1 in 1,000 people in most western countries. The inflammatory lesions …

Introduction Cerebrospinal fluid collection by lumbar puncture (LP) is performed in the
diagnostic workup of several neurological brain diseases. Reluctance to perform the …

Background: Levels of CXCL13, a potent B-cell chemoattractant, are elevated in the
cerebrospinal fluid (CSF) during multiple sclerosis (MS) and are associated with markers of …

Background Autologous haematopoietic stem cell transplantation (HSCT) is a viable option
for treatment of aggressive multiple sclerosis (MS). No randomised controlled trial has been …

The choice of appropriate control group (s) is critical in cerebrospinal fluid (CSF) biomarker
research in multiple sclerosis (MS). There is a lack of definitions and nomenclature of …

Summary Background Mesenchymal stem cells (MSCs), also known as mesenchymal
stromal cells, have been proposed as a promising therapeutic option for people with multiple …

Over the recent years, the treatment of multiple sclerosis (MS) and neuromyelitis optica
spectrum disorder (NMOSD) has evolved very rapidly and a large number of disease …