User profiles for "author:Emily Beswick"
 | Emily BeswickUniversity of Edinburgh Verified email at ed.ac.uk Cited by 176 |
Clinical trials in amyotrophic lateral sclerosis: a systematic review and perspective
C Wong, M Stavrou, E Elliott, JM Gregory… - Brain …, 2021 - academic.oup.com
Amyotrophic lateral sclerosis is a progressive and devastating neurodegenerative disease.
Despite decades of clinical trials, effective disease-modifying drugs remain scarce. To …
Despite decades of clinical trials, effective disease-modifying drugs remain scarce. To …
[HTML][HTML] A systematic review of non-motor symptom evaluation in clinical trials for amyotrophic lateral sclerosis
Background Amyotrophic lateral sclerosis (ALS) is increasingly recognised as a multi-
system disorder, presenting with common and impactful non-motor symptoms, such as …
system disorder, presenting with common and impactful non-motor symptoms, such as …
[HTML][HTML] A systematic review of neuropsychiatric and cognitive assessments used in clinical trials for amyotrophic lateral sclerosis
Background Up to 50% of people with amyotrophic lateral sclerosis (ALS) experience
cognitive dysfunction, whilst depression and anxiety are reported in up to 44% and 33 …
cognitive dysfunction, whilst depression and anxiety are reported in up to 44% and 33 …
[HTML][HTML] A systematic review of digital technology to evaluate motor function and disease progression in motor neuron disease
Amyotrophic lateral sclerosis (ALS) is the most common subtype of motor neuron disease
(MND). The current gold-standard measure of progression is the ALS Functional Rating …
(MND). The current gold-standard measure of progression is the ALS Functional Rating …
[HTML][HTML] Digital Endpoints for Assessing Instrumental Activities of Daily Living in Mild Cognitive Impairment: Systematic Review
L Lawson, R Mc Ardle, S Wilson, E Beswick… - Journal of Medical …, 2023 - jmir.org
Background Subtle impairments in instrumental activities of daily living (IADLs) can be a key
predictor of disease progression and are considered central to functional independence …
predictor of disease progression and are considered central to functional independence …
[HTML][HTML] The Patient Health Questionnaire (PHQ-9) as a tool to screen for depression in people with multiple sclerosis: a cross-sectional validation study
E Beswick, S Quigley, P Macdonald, S Patrick… - BMC psychology, 2022 - Springer
Background: Depression has a point prevalence of 25% and lifetime prevalence of 50% in
people with multiple sclerosis (pwMS). Due to accessibility and brevity, the 9-item Patient …
people with multiple sclerosis (pwMS). Due to accessibility and brevity, the 9-item Patient …
[HTML][HTML] Factoring in the Complexity of the Cystic Fibrosis Lung to Understand Aspergillus fumigatus and Pseudomonas aeruginosa Interactions
Pseudomonas aeruginosa has long been established as the most prevalent respiratory
pathogen in Cystic Fibrosis (CF) patients, with opportunistic infection causing profound …
pathogen in Cystic Fibrosis (CF) patients, with opportunistic infection causing profound …
Clinical audit research and evaluation of motor neuron disease (CARE-MND): a national electronic platform for prospective, longitudinal monitoring of MND in …
D Leighton, J Newton, S Colville, A Bethell… - … Lateral Sclerosis and …, 2019 - Taylor & Francis
Abstract Objectives: Launched in 1989, the Scottish Motor Neuron Disease Register
(SMNDR) has provided a resource for prospective clinical data collection. However, in 2015 …
(SMNDR) has provided a resource for prospective clinical data collection. However, in 2015 …
[HTML][HTML] Genotype–phenotype characterisation of long survivors with motor neuron disease in Scotland
DJ Leighton, M Ansari, J Newton, D Parry, E Cleary… - Journal of …, 2023 - Springer
Background We investigated the phenotypes and genotypes of a cohort of 'long-
surviving'individuals with motor neuron disease (MND) to identify potential targets for …
surviving'individuals with motor neuron disease (MND) to identify potential targets for …
[HTML][HTML] A systematic review and narrative analysis of digital speech biomarkers in Motor Neuron Disease
M Bowden, E Beswick, J Tam, D Perry, A Smith… - NPJ Digital …, 2023 - nature.com
Abstract Motor Neuron Disease (MND) is a progressive and largely fatal neurodegeneritve
disorder with a lifetime risk of approximately 1 in 300. At diagnosis, up to 25% of people with …
disorder with a lifetime risk of approximately 1 in 300. At diagnosis, up to 25% of people with …