Antifibroblast growth factor receptor 3 antibodies identify a subgroup of patients with sensory neuropathy

JC Antoine, N Boutahar, F Lassablière… - Journal of Neurology …, 2015 - jnnp.bmj.com
Background Immunological mechanisms are suspected in sensory neuropathy (SN)
occurring with systemic autoimmune diseases and in some idiopathic cases, but so far there …

Brain‐derived neurotrophic factor inhibits cell cycle reentry but not endoplasmic reticulum stress in cultured neurons following oxidative or excitotoxic stress

N Boutahar, E Reynaud… - Journal of …, 2010 - Wiley Online Library
Neurotrophins protect neurons against glutamate and oxidative stress, but the underlying
mechanism remains unclear. We investigated the neuroprotective role of the neurotrophin …

Differential effect of oxidative or excitotoxic stress on the transcriptional profile of amyotrophic lateral sclerosis‐linked mutant SOD1 cultured neurons

N Boutahar, A Wierinckx… - Journal of …, 2011 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a progressive, lethal, degenerative disorder of motor
neurons. The causes of most cases of ALS are as yet undefined. In a previous study, it was …

Clinical characterisation of sensory neuropathy with anti-FGFR3 autoantibodies

Y Tholance, CP Moritz, C Rosier, K Ferraud… - Journal of Neurology …, 2020 - jnnp.bmj.com
Objective Sensory neuropathies (SNs) are often classified as idiopathic even if
immunological mechanisms can be suspected. Antibodies against the intracellular domain …

Timing differences of signaling response in neuron cultures activated by glutamate analogue or free radicals

N Boutahar, E Reynaud, F Lassabliere, J Borg - Brain research, 2008 - Elsevier
Oxidative stress and excitotoxicity are both involved in the pathogenesis of neuronal
degenerative diseases like ALS. In order to compare their action, some key proteins …

Anti-FGFR3 antibody epitopes are functional sites and correlate with the neuropathy pattern

Y Tholance, JC Antoine, L Mohr, M Jung… - Journal of …, 2021 - Elsevier
Antibodies against FGFR3 define a subgroup of sensory neuropathy (SN). The aim of this
study was to identify the epitope (s) of anti-FGFR3 autoantibodies and potential epitope …

Completing the immunological fingerprint by refractory proteins: autoantibody screening via an improved immunoblotting technique

CP Moritz, Y Tholance, C Rosier… - PROTEOMICS …, 2019 - Wiley Online Library
Purpose Identifying autoantigens of serological autoantibodies requires expensive methods,
such as protein microarrays or IP+ MS. Thus, sera are commonly pre‐screened for …

[CITATION][C] Sensory neuronopathy associated anti-FGFR3 antibodies induce neuronal cell death through MAP kinase and autophagy pathways

Y Nasser… - JOURNAL OF …, 2021 - … ST, HOBOKEN 07030-5774, NJ USA

[CITATION][C] The role and molecular mechanisms of the anti-FGFR3 antibody, a biomarker of sensory neuropathies inducing neuronal death

Y Nasser… - JOURNAL OF …, 2020 - … ST, HOBOKEN 07030-5774, NJ USA

[CITATION][C] Argonaute autoantibodies as biomarkers for a dysimmune context in peripheral neuropathies

C Moritz, Le Duy Do… - JOURNAL OF …, 2021 - … ST, HOBOKEN 07030-5774, NJ USA