Temporal lobe epilepsy (TLE) accompanied by hippocampal sclerosis (HS) is the type of
epilepsy most frequently operated on. The predictors for long-term seizure freedom after …

Purpose: The mechanisms of drug resistance in epilepsy are only incompletely understood.
According to a current concept, overexpression of drug efflux transporters at the blood–brain …

Objectives: To identify predictive factors for the seizure-free outcome of vagus nerve
stimulation (VNS). Methods: All 47 patients who had undergone VNS implantation at one …

Object The goal of this study was to evaluate the long-term outcome of patients who
underwent extratemporal epilepsy surgery and to assess preoperative prognostic factors …

Previously, we reported on inter-individual and gender specific variations of LINE-1
methylation in healthy individuals. In this study, we investigated whether this variability could …

Purpose: The anticonvulsant effects of the novel antiepileptic drug (AED) levetiracetam
(LEV) were tested in neocortical slice preparations from 23 patients who underwent surgery …

OBJECTIVES:: To identify prognostic factors which predict the outcome 2 years after TLE
surgery in those patients who were not seizure-free at the 6-month postoperative …

Background/Aims: Exogenous hyperammonemia is known to decrease the plasma levels of
branched-chain amino acids (BCAA). To investigate whether changes in intracellular amino …

OBJECTIVES: In the current classification of epilepsies two forms of temporal lobe epilepsy
(TLE) were included: mesial and lateral (neocortical) TLE. We aimed at identifying …

Causes underlying inter-individual variations in DNA methylation profiles among normal
healthy populations are not thoroughly understood. To investigate the contribution of genetic …