User profiles for "author:Fardad Afshari"

Fardad T. Afshari

Dept of Neurosurgery, Birmingham Children's Hospital
Verified email at nhs.net
Cited by 1238

Proteoglycans in the central nervous system: plasticity, regeneration and their stimulation with chondroitinase ABC

JCF Kwok, F Afshari, G Garcia-Alias… - Restorative neurology …, 2008 - content.iospress.com
After injury to the mammalian central nervous system (CNS), neurons are not able to
regenerate their axons and recovery is limited by restricted plasticity. Axon regeneration is …

Extrinsic and intrinsic factors controlling axonal regeneration after spinal cord injury

FT Afshari, S Kappagantula… - Expert reviews in molecular …, 2009 - cambridge.org
Spinal cord injury is one of the most devastating conditions that affects the central nervous
system. It can lead to permanent disability and there are around two million people affected …

Schwann cell migration is integrin‐dependent and inhibited by astrocyte‐produced aggrecan

FT Afshari, JC Kwok, L White, JW Fawcett - Glia, 2010 - Wiley Online Library
Schwann cells transplantation has considerable promise in spinal cord trauma to bridge the
site of injury and for remyelination in demyelinating conditions. They support axonal …

Astrocyte-produced ephrins inhibit schwann cell migration via VAV2 signaling

FT Afshari, JC Kwok, JW Fawcett - Journal of Neuroscience, 2010 - Soc Neuroscience
Schwann cells are a promising candidate for bridging spinal cord injuries and remyelinating
axons. However, grafted Schwann cells show little intermingling with host astrocytes and …

[HTML][HTML] Global perspectives on task shifting and task sharing in neurosurgery

FC Robertson, IN Esene, AG Kolias, T Khan… - World neurosurgery …, 2020 - Elsevier
Background Neurosurgical task shifting and task sharing (TS/S), delegating clinical care to
non-neurosurgeons, is ongoing in many hospital systems in which neurosurgeons are …

Impact of COVID-19 pandemic on surgical neuro-oncology multi-disciplinary team decision making: a national survey (COVID-CNSMDT Study)

SJ Price, A Joannides, P Plaha, FT Afshari… - BMJ open, 2020 - bmjopen.bmj.com
Objectives Pressures on healthcare systems due to COVID-19 has impacted patients without
COVID-19 with surgery disproportionally affected. This study aims to understand the impact …

Interpretation of telemetric intracranial pressure recordings in people with idiopathic intracranial hypertension after shunt implantation

FT Afshari, M Samara, KZ Thant, ME Byrne… - Acta …, 2023 - Springer
Background The M. scio telesensor (Aesculap-Miethke, Germany) is a device integrated
within a ventriculoperitoneal (VP) shunt for non-invasive measurement of the intracranial …

Proposal for establishment of the UK Cranial Reconstruction Registry (UKCRR)

AG Kolias, DO Bulters, CJ Cowie… - British Journal of …, 2014 - Taylor & Francis
Background. The increasing utilisation of decompressive craniectomy for traumatic brain
injury and stroke has led to an increase in the number of cranioplasties undertaken …

The implementation of an external ventricular drain care bundle to reduce infection rates

SS Talibi, AHD Silva, FT Afshari, J Hodson… - British Journal of …, 2020 - Taylor & Francis
Background: The main complication of external ventricular drains (EVD) is infection.
Implementation of evidence-based guidelines for central venous catheter (CVC) care …

Integrin activation or alpha9 expression allows retinal pigmented epithelial cell adhesion on Bruch's membrane in wet age-related macular degeneration

FT Afshari, JC Kwok, MR Andrews, B Blits, KR Martin… - Brain, 2010 - academic.oup.com
Retinal pigment epithelial cell malfunction is a causative feature of age-related macular
degeneration, and transplantation of new retinal pigment epithelial cells is an attractive …