An overview of the following six cortical zones that have been defined in the presurgical
evaluation of candidates for epilepsy surgery is given: the symptomatogenic zone; the …

We convened an international group of experts to standardize definitions of New‐Onset
Refractory Status Epilepticus (NORSE), Febrile Infection‐Related Epilepsy Syndrome …

Epilepsy is a common chronic neurological disorder affecting approximately 8 out of 1000
people. Its pathophysiology, however, has remained elusive in many regards …

Background Detailed neuropathological information on the structural brain lesions
underlying seizures is valuable for understanding drug-resistant focal epilepsy. Methods We …

Abstract We identified 15q13. 3 microdeletions encompassing the CHRNA7 gene in 12 of
1,223 individuals with idiopathic generalized epilepsy (IGE), which were not detected in …

Purpose: To determine the incidence and case‐fatality rate of status epilepticus (SE) in
adults in Hessen, Germany, we performed a prospective, population‐based study from July …

Idiopathic generalized epilepsies account for 30% of all epilepsies. Despite a predominant
genetic aetiology, the genetic factors predisposing to idiopathic generalized epilepsies …

Objective: To evaluate the efficacy and safety of perampanel 2, 4, and 8 mg/day added to 1–
3 concomitant antiepileptic drugs (AEDs) in patients with uncontrolled partial-onset seizures …

Purpose: To evaluate the efficacy and safety of lacosamide (200 and 400 mg/day) when
added to one to three concomitant antiepileptic drugs (AEDs) in patients with uncontrolled …

Background Surgery is a widely accepted treatment option for drug-resistant focal epilepsy.
A detailed analysis of longitudinal postoperative seizure outcomes and use of antiepileptic …