Sixteen normal volunteers were studied with [F-18] fluorodeoxyglucose and positron
emission tomography scans during behavioral activation with a verbal fluency test, and 35 …

Fingolimod (FTY) is the first oral medication approved for treatment of relapsing–remitting
multiple sclerosis (RRMS). Its effectiveness and safety were confirmed in several phase III …

• Thirty-one patients with probable Alzheimer's disease and 11 patients with memory
disorders, attributable to multiple cerebral infarctions, were studied using 18-F …

Background Cognitive impairment could affect quality of life for patients with multiple
sclerosis (MS), and cognitive function may be correlated with several factors such as …

In 76 normal volunteers studied by positron emission tomography, with [18F]
fluorodeoxyglucose, CMRglu was significantly lower in the elderly as compared with young …

Objectives To determine the frequency, distribution, and clinical features of Parkinson
disease (PD) withPINK1mutations. Design Retrospective clinical and genetic review. Setting …

In order to clarify the clinical and genetic features of SCA6, we retrospectively analyzed 140
patients. We observed an inverse correlation between the age of onset and the length of the …

To investigate local metabolic and hemodynamic interrelationships during functional
activation of the brain, paired studies of local cerebral glucose utilization (lCMRGlc) and …

In Parkinson's disease (PD), sudden unexpected sleep episodes and excessive daytime
sleepiness (EDS) while driving and engaging in social activities are important problems. We …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by a
selective loss of motor neurons in the brain and spinal cord. Multiple toxicity pathways, such …