User profiles for "author:Graham P Taylor"

Graham P Taylor

Professor of Human Retrovirology, Imperial College London
Verified email at imperial.ac.uk
Cited by 42126

HTLV-1-associated myelopathy/tropical spastic paraparesis

CRM Bangham, A Araujo, Y Yamano… - Nature reviews Disease …, 2015 - nature.com
Human T-lymphotropic virus 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis
(HAM/TSP) is a progressive disease of the CNS that causes weakness or paralysis of the …

Natural history of adult T-cell leukemia/lymphoma and approaches to therapy

GP Taylor, M Matsuoka - Oncogene, 2005 - nature.com
After cell-to-cell transmission, HTLV-I increases its viral genome by de novo infection and
proliferation of infected cells. Proliferation of infected cells is clonal and persistent in vivo …

[HTML][HTML] Community transmission and viral load kinetics of the SARS-CoV-2 delta (B. 1.617. 2) variant in vaccinated and unvaccinated individuals in the UK: a …

A Singanayagam, S Hakki, J Dunning… - The lancet infectious …, 2022 - thelancet.com
Summary Background The SARS-CoV-2 delta (B. 1.617. 2) variant is highly transmissible
and spreading globally, including in populations with high vaccination rates. We aimed to …

Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton

T Igakura, JC Stinchcombe, PKC Goon, GP Taylor… - Science, 2003 - science.org
Cell contact is required for efficient transmission of human T cell leukemia virus–type 1
(HTLV-I) between cells and between individuals, because naturally infected lymphocytes …

[HTML][HTML] Definition, prognostic factors, treatment, and response criteria of adult T-cell leukemia-lymphoma: a proposal from an international consensus meeting

K Tsukasaki, O Hermine, A Bazarbachi… - Journal of Clinical …, 2009 - ncbi.nlm.nih.gov
Adult T-cell leukemia-lymphoma (ATL) is a distinct peripheral T-lymphocytic malignancy
associated with a retrovirus designated human T-cell lymphotropic virus type I (HTLV-1). The …

HLA alleles determine human T-lymphotropic virus-I (HTLV-I) proviral load and the risk of HTLV-I-associated myelopathy

KJM Jeffery, K Usuku, SE Hall… - Proceedings of the …, 1999 - National Acad Sciences
The risk of disease associated with persistent virus infections such as HIV-I, hepatitis B and
C, and human T-lymphotropic virus-I (HTLV-I) is strongly determined by the virus load …

Treatment of tuberculosis in HIV-infected persons in the era of highly active antiretroviral therapy

GL Dean, SG Edwards, NJ Ives, G Matthews, EF Fox… - Aids, 2002 - journals.lww.com
Treatment of tuberculosis in HIV-infected persons in the era... : AIDS Treatment of tuberculosis
in HIV-infected persons in the era of highly active antiretroviral therapy : AIDS Log in or Register …

Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19

RS Thwaites, A Sanchez Sevilla Uruchurtu… - Science …, 2021 - science.org
While it is now widely accepted that host inflammatory responses contribute to lung injury,
the pathways that drive severity and distinguish coronavirus disease 2019 (COVID-19) from …

Earlier initiation of ART and further decline in mother-to-child HIV transmission rates, 2000–2011

CL Townsend, L Byrne, M Cortina-Borja, C Thorne… - Aids, 2014 - journals.lww.com
Objectives: To analyze mother-to-child HIV transmission (MTCT) rates over time in light of
changes in management, demographic, and pregnancy characteristics. Design: Population …

[HTML][HTML] Cross-reactive memory T cells associate with protection against SARS-CoV-2 infection in COVID-19 contacts

R Kundu, JS Narean, L Wang, J Fenn, T Pillay… - Nature …, 2022 - nature.com
Cross-reactive immune responses to SARS-CoV-2 have been observed in pre-pandemic
cohorts and proposed to contribute to host protection. Here we assess 52 COVID-19 …