Mucopolysaccharidosis IVA (MPS IVA, Morquio A disease) is an inherited lysosomal storage
disorder that features skeletal chondrodysplasia caused by deficiency of N …

Abstract Mucopolysaccharidosis IVA (MPS IVA) is an autosomal recessive disorder caused
by a deficiency of N-acetylgalactosamine-6-sulfate sulfatase (GALNS), leading to …

Glycosaminoglycans (GAGs) are accumulated in various organs in both
mucopolysaccharidoses (MPS) and mucolipidoses II and III (ML II and III). MPS and ML II …

Abstract Mucopolysaccharidosis I (MPS I) is an autosomal recessive disorder caused by
deficiency of α-L-iduronidase leading to accumulation of its catabolic substrates, dermatan …

Abstract Mucopolysaccharidosis type IVA (MPS IVA, Morquio A disease), a progressive
lysosomal storage disease, causes skeletal chondrodysplasia through excessive storage of …

Mental stress, such as anxiety and conflict, causes physiological changes, such as changes
in autonomic nervous activity and gastric ulcers. In addition, stress induces glucocorticoids …

Neuronal nicotinic acetylcholine receptors (nAChRs) are composed of an assembly
between at least seven alpha (α2–α7, α9) and three beta (β2–β4) subunits in mammals. The …

We have tested an acidic oligopeptide-based targeting system for delivery of enzymes to
tissues, especially bone and brain, in a murine mucopolysaccharidosis type VII (MPS VII) …

Children with mucopolysaccharidoses (MPS) grow poorly and become physically
handicapped because of systemic bone disease. For children with skeletal dysplasias, such …

Mucopolysaccharidosis IVA (MPS IVA) is an autosomal recessive disorder caused by a
deficiency of N-acetylgalactosamine-6-sulfate sulfatase (GALNS). The aims of this study …